Saturday, April 15, 2017

Malaria Basics: A Crash Course

Before coming to Cameroon, I knew very little about malaria. All I knew was from my undergraduate public health classes, as well as from previous visits to doctors before traveling. I knew it was a disease transmitted by mosquitoes that primarily affects individuals in tropical and sub-tropical climates, and that it kills a disproportionate number of people in African countries every year. And that was pretty much it. Little did I know that years later, malaria would be the primary focus of my life for a whole month—and likely two years more—during my Peace Corps service.
            I became fascinated with malaria the first day we started talking about it during PST. Obviously, from the start we were told certain things about malaria, like the importance of taking our prophylaxis and sleeping under a bed net every night to prevent it. However, I’ve always been interested in the why of things like this, the biological mechanisms behind things (okay yeah so I’m a bit of a science nerd), and so it wasn’t until our malaria unit in PST that I really became interested in the disease.
            Here, we learned that the disease malaria is caused by a parasite called Plasmodium. Though there are several types of Plasmodium that cause the disease, the most deadly—and commonly found in sub-Saharan Africa—is known as Plasmodium falciparum. The disease is transferred by the bite of a female Anopheles mosquito that is infected with the parasite. This specific mosquito prefers warm environments, and only bites between the hours of around 8pm and 4am. Our trainer explained that this is why bed nets are such an effective method of preventing malaria—because the mosquito that transmits the parasite comes out during the night when most people are asleep, if you just cover yourself with a bed net during that time, you’re less likely to get bitten. This was the ‘why’ I had been looking for!
A properly hung bed net

            Next, we learned about the transmission cycle and manifestation of the disease. Here, we learned that after the infected mosquito bites someone, the parasite enters the body and stays in the liver. The parasite can stay dormant in the liver for anywhere between one and four weeks. During this time, the infected person does not experience any symptoms, and is not contagious (i.e. cannot transmit the parasite to another mosquito, which is how the disease is spread from person to person). Then, the parasite leaves the liver and begins infecting red blood cells, which it uses as sites of reproduction. After 2-3 days, the red blood cells explode, releasing new parasites into the blood stream, where they begin infecting other red blood cells. When these red blood cells explode, toxins are released into the body, which cause the first telltale symptoms of malaria: high fever and severe headaches. Because so many red blood cells are destroyed during this process, it is common for people with malaria to become anemic very quickly. At around the same time that the parasites begin infecting red blood cells, other parasites become capable of being transmitted to other mosquitoes, which starts the transmission cycle all over again. Because the symptoms occur with the spread of the disease from the liver to the red blood cells, there is very little time between a person becoming symptomatic and becoming capable of transmitting the disease to another mosquito, and eventually another person. This is why immediate treatment is so important for those diagnosed with malaria!
A great graphic to help better understand the malaria transmission cycle

            Besides the scientific stuff, we learned the real-life effects that malaria can have on individuals, families, nations, and continents. Here we learned that malaria is the cause of 660,000 deaths each year, 90% of which occur in sub-Saharan Africa. We also learned that every minute, a child dies due to malaria, and that malaria is the primary cause of missed days of school among students in Africa, with approximately 10 million days of school being missed each year due to the disease. We also learned that malaria is the primary cause of morbidity—the number of people living with an illness—and mortality—the number of people who die due to an illness—amongst vulnerable populations in Cameroon. These groups include children under age 5, pregnant women, and people living with HIV. The malaria morbidity rate is 52% amongst children under the age of 5 and 38% amongst pregnant women. In Cameroon, malaria is the primary cause of hospitalizations and of consultations at health centers, as well as the primary cause of child mortality. Here, a child dies every four hours from malaria.

            Now I’m sure to many of you, malaria seems like a foreign thing that you will never have to confront in your whole life. Which for some of you may actually be the case. However, what some of you may not know is that malaria is not just a problem in sub-Saharan Africa. It is a problem all over the world, and at one time, was a problem in nearly every country, including—you guessed it—the good ol’ United States of America. Yup, that’s right—malaria wasn’t eradicated from the United States until 1951. This means that some of your grandparents—or maybe even your parents—had or knew someone who had malaria while living in the US. Between 1946 and 1951, malaria was eradicated from most of the world, except in sub-Saharan Africa. Why is that? Unfortunately, though the global efforts to defeat malaria were strong and united, they for the most part completely ignored sub-Saharan Africa. This is likely a major explanation for why malaria has not been eradicated from this region yet, despite the fact that it has been eradicated from many other parts of the world.
            So at this point, some of you may be thinking, “well maybe it’s just impossible to eradicate malaria from that region!” While that may be an easy way to get out of caring about the problem, it’s actually not true! After the world finally started paying attention to and addressing malaria in sub-Saharan Africa, by 2008, malaria deaths in 10 sub-Saharan African countries fell by more than 50%. So yes, though there may be more challenges in addressing malaria in these populations, completely eradicating it is by no means impossible. Those of us doing malaria work just need to keep pushing, and keep forcing the world to pay attention to the problem. Though malaria may not seem as scary or exciting to the world as the Ebola crisis, it’s a terrifying reality for millions of people in sub-Saharan Africa, and it needs to be addressed just as ferociously as the Ebola crisis was.
            So, what am I doing to address the problem in my community? I’m glad you asked! Over the past month or so, I’ve been working with the chief of my health center to plan a project to address malaria prevention in my community and those surrounding it. When I come back from this gardening training I’ve been at—something I promise I’ll write about later! —we’re gonna really get the ball rolling. Once I get back, we will have a peer educator training for 10 community members that have already been trained by Plan Cameroon as Community Health Agents (Agents de Santé Communautaire, or ASC in francophone regions). Here, we will introduce the goal and steps of our project, as well as teach them more in-depth information about malaria, prevention, and the economic losses caused by malaria in our community and around the world. After finishing the training—including the distribution of some handy PC-certified certificates—we will begin the next phase of the project. Here, the ASCs will be assigned zones within our village, where they will be responsible for going door-to-door and performing surveys with community members. These surveys are designed to gauge community members’ knowledge of malaria basics, measure their usage of preventative measures, and scout out houses where bed nets are missing or have not been hung up yet. After finishing the surveys, the ASCs will begin the third part of the project. Here, they will go back to their zones, and continue going door-to-door. This time, however, they will assist people in hanging up their nets, and ensuring that every house they visit has an appropriate number of nets hung up for the number of people living there. After helping with net installation, they will talk to community members about malaria, including information about transmission, prevention, vulnerable populations, and the costs and losses for families and the community due to malaria. Finally, a month later, the ASCs will initiate the final step of the project. Here, they will go back to their zones for a final time with the same survey as used in the beginning. They will ask the same questions to ensure that community members have retained the information given to them, and will check in on families to see how their bed net usage is going. Though this project hasn’t started yet, I’m feeling really excited about it, and am sincerely hoping that it will create some positive change in my community. I’ll be sure to keep you updated with the project when it’s finished!

            Feeling inspired by my post and are just itching (no pun intended) to do something yourself? Awesome! If you’re looking for ways to get involved in the fight against malaria, I have a few ideas for you. First, check out some cool organizations with malaria eradication as their primary goal, such as Stomp Out Malaria and Roll Back Malaria. If you have a few extra dollars lying around, maybe even make a donation to one of these organizations, or see if there’s a way you can donate bed nets or something more specific. Next, go public! Post a Facebook status about how you donated to one of these organizations, or with a cool fact you learned about malaria from me or anywhere else. If you’re mentioning one of these orgs, be sure to tag them so other people can visit their pages! Talk to your weird aunt at your next family party about malaria and its impact on the world—heck, it may even help you avoid that awkward conversation of why you’re still single or why you don’t care that it might be hard to find a “real job” with a degree in Art History. No matter what you do, MAKE THE WORLD KNOW that malaria is still a major problem, and that it’s not going to go away unless we all work together to fight it. Keep fightin the bite, my friends, and let me know if you ever wanna chat more about malaria!    
The official logo for #StompOutMalaria, a malaria initiative powered by Peace Corps volunteers in various African countries

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